Russian fourth seed Daniil Medvedev eased past home favorite Alexei Popyrin in straight sets to seal his spot in the Australian Open fourth round.

Medvedev, 23, outclassed the unseeded Popyrin 6-4 6-3 6-2 on Rod Laver Arena as he booked a match-up with Swiss 2014 champion Stan Wawrinka in the last 16.

Wawrinka, seeded 15th, had the luxury of an early finish in his third-round match as big-serving American opponent John Isner retired while 6-4 4-1 down.

Medvedev faced minimal resistance in his encounter with Popyrin as the 20-year-old Australian showed little sign of springing an upset in front of his home crowd. (RT)