Turkish ministers on Friday said the death toll in an explosion at a fireworks factory in Turkey’s northwestern province of Sakarya rose to four and the number of wounded people to 108, according to Xinhua.

Speaking to reporters on the scene in the Hendek district, Interior Minister Suleyman Soylu said so far four people were killed, and search and rescue operation is continuing.

Health Minister Fahrettin Koca noted that a total of 108 people were wounded and rushed to hospitals, noting that 48 of them, with minor injuries, were later discharged.

A huge explosion occurred at 11:15 a.m. local time (0815 GMT) at the factory, which contains 110 tons of explosive materials.

The main blast was followed by a series of other explosions, preventing firefighters from controlling the fire and launching a rescue operation.

The authorities urged the citizens to leave the region and stay indoors as the chemicals in the smoke can affect health.

The Disaster and Emergency Management Authority announced that the incident should be considered as an industrial accident, and no radiation source has been detected at the factory.